

One story revealed Jessica to be the Viper's daughter, though it was later retconned that some magical force was toying with their minds.

She later severed ties with Hydra and from then onwards became known as Viper after killing the previous supervillain codenamed Viper (Jordan Strike) to usurp his codename and leadership of the Serpent Squad. She rose through the ranks of Hydra, eventually becoming its leader under the codename Madame Hydra, and frequently came into conflict with Captain America and S.H.I.E.L.D. Among twelve other girls, Ophelia was taken in by Hydra and raised by Kraken, eventually becoming Kraken's best student.

Ophelia Sarkissian was orphaned as a child in Hungary. Alter Ego: Ophelia Sarkkissian, Madame Hydra I First Appearance: Captain America #110 (February, 1969)
